Neuro-ophthalmology Illustrated Chapter 20 – Conditions Commonly Encountered in Neuro-ophthalmology 5

Questions:
38. What type of iris nodules are present in Neurofibromatosis Type 1, and  Neurofibromatosis Type 2?
39. What are the ocular or CNS manifestations of Neurofibromatosis Type 1?
40. What are the ocular or CNS manifestations of Neurofibromatosis Type 2?
41. What is the classic findings triad in tuberous sclerosis?
42. What is the most prominent ocular manifestation of Tuberous sclerosis?
43. What autosomal dominant condition is associated with multiple, bilateral retinal angiomas and intracranial cerebellar hemangioblastomas?
44. What condition should be suspected in a patient with findings of telangiectasias of the conjunctival vessels and oculomotor apraxia?
45. A patient has an upper eyelid hemangioma, intraocular hypertension, and homonymous hemianopia, what condition is likely to be present?
46. What are the ocular manifestations of Sturge-Weber syndrome?
47. What are the findings of the Wyburn-Mason Syndrome?
48. What are the findings of the Klippel-Trenaunay-Weber Syndrome?

Neuro-ophthalmology Illustrated Chapter 20 – Conditions Commonly Encountered in Neuro-ophthalmology 3

Questions:
27. Multiple sclerosis is more common in:
1. Men or Women? 
2. African-Americans, Caucasians, or Hispanics?
28. What is Lhermitte sign and is it a classic finding in Multiple sclerosis?
29. What are the common eye symptoms of multiple sclerosis?
30. What is the 15-year risk of multiple sclerosis after an initial episode of optic neuritis:
1. overall 
2. with no MRI lesions
3. with 1 MRI lesions 
4. with 2 MRI lesions
5. with ≥ 3 MRI lesions
31. How common is mild-to-severe eye pain in optic neuritis?
32. What are the characteristics of Neuromyelitis Optica (Devic disease)?
33. What treatments are useful Neuromyelitis Optica?

Neuro-ophthalmology Illustrated Chapter 20 – Conditions Commonly Encountered in Neuro-ophthalmology 2

Questions: 
16.  What condition should be considered in any patient over 50 with transient or constant diplopia?
17. What condition should be considered in any patient over 50 with headaches
18. Is Cranial Arteritis common, uncommon, or rare among Blacks, Hispanics, Asians, and Whites?
19. What percent of patients will have premonitory visual symptoms, usually within the week preceding permanent visual loss from Cranial Arteritis?
20. What are the 7 ophthalmic signs in a patient with anterior ischemic optic neuropathy that are highly suggestive of Cranial Arteritis?
21. In what percentage of patients with Cranial Arteritis will the ESR be normal?
22. Is the CRP ever normal in Cranial Arteritis?
23. What other blood tests may be elevated in Cranial Arteritis?
24. How long will patients with Cranial Arteritis generally need to be treated with oral steroids?
25. At what rate should oral prednisone be tapered in Cranial Arteritis?
26. What test is the only test that confirms the diagnosis of temporal arteritis?

Neuro-ophthalmology Illustrated Chapter 9 – Disk Edema 3

Questions:
34. What are the symptoms and signs of idiopathic intracranial hypertension (IIH)?
35. What are the diagnostic criteria for IIH?
36. What is the ideal imaging test when evaluating a patient with presumed papilledema?
37. A patient with bilateral disc swelling has a normal brain MRI. What test should be done next?
38. What should one consider if the headaches of IIH do not improve (at least transiently) after a lumbar puncture?
39. What does a normal Brain MRI in the setting of papilledema suggest?
40. What should be evaluated next in a patient with bilateral swollen discs, normal BP, normal CT with and without contrast, LP opening pressure >250mm and normal or abnormal CSF contents?
41. What should be evaluated next in a patient with bilateral swollen discs, normal BP, normal MRI with and without contrast, LP opening pressure >250mm and normal or abnormal CSF contents? 
42. What items are most commonly associated with IIH?
43. What condition can mimic the symptoms of cerebral venous thrombosis?
44. What can early recognition of cerebral venous thrombosis prevent?
45. Should papilledema from a meningeal process or cerebral venous thrombosis be classified as IIH?
46. What are the goals of IIH management?
47. What are the main factors that drive the management of IIH?
48. What MRI findings are supportive of the diagnosis of IIH?
49. When the predominant symptom of a patient with IIH is severe headaches, which surgical procedure is preferred?
50. How often does a lumboperitoneal or ventriculoperitoneal shunt need to be repaired?
51. When the predominant symptom of a patient with IIH is vision loss and headaches are no more than mild, which surgical procedure is preferred?
52. Does optic nerve sheath fenestration usually need to be performed on both optic nerves?
53. How often does optic nerve sheath fenestration fail?

Neuro-ophthalmology Illustrated Chapter 9 – Disk Edema 2

Questions:
17. Once optic disc edema is confirmed, what should be determined?
18. In anterior optic neuropathy with disk edema, is visual acuity usually decreased?
19. In papilledema is visual acuity usually decreased?
20. In anterior optic neuropathy with disk edema is color vision usually decreased?
21. In papilledema is color vision usually decreased?
22. What are the usual characteristics of visual field defects in anterior optic neuropathy with disk edema?
23. What are the usual characteristics of visual field defects in papilledema
24. Is anterior optic neuropathy with disk edema usually unilateral?
25. Is papilledema usually unilateral?
26. What findings are often associated with papilledema?
27. Does the absence of disc edema rule-out raised intracranial pressure in a patient presenting with headache?
28. What visual symptoms are associated with papilledema?
29. When is central visual acuity loss experienced in papilledema, early or late?
30. What type of visual field defect is found initially with papilledema?
31. What type of visual field loss is experienced in long-standing papilledema?
32. Can visual loss from papilledema occur with any cause of papilledema?
33. What should be assessed next in a patient found to have papilledema?

Neuro-ophthalmology Illustrated Chapter 9 – Disk Edema 1

Questions:
1. What is the term reserved for optic disk swelling with increased intracranial pressure?
2. Does pseudoedema of the optic disk have elevated optic nerve head?
3. Does pseudoedema of the optic disk have sharp margins?
4. Does pseudoedema of the optic disk have obscured vessels?
5. Does pseudoedema of the optic disk have a central cup?
6. Does pseudoedema of the optic disk have anomalous retinal vasculature?
7. Does pseudoedema of the optic disk leak on FA?
8. Does pseudoedema of the optic disk have peripapillary hemorrhages and exudates?
9. Does pseudoedema of the optic disk have venous dilation and tortuosity? 10. Does true disc edema of the optic disk have elevated optic nerve head?
11. Does true disc edema of the optic disk have sharp margins?
12. Does true disc edema of the optic disk have obscured vessels?
13. Does true disc edema of the optic disk have venous dilation and tortuosity?
14. Does true disc edema of the optic disk have anomalous retinal vasculature?
15. Does true disc edema of the optic disk have peripapillary hemorrhages and exudates?
16. Does true disc edema of the optic disk leak on FA?

Neuro-ophthalmology Illustrated Chapter 8 – Optic Neuropathies 11

Questions:
130. What type of traumatic optic neuropathy may require emergent treatment?
131. What is the management of indirect traumatic optic neuropathy?
132. What should be done in all cases of head trauma?
133. What potential alternative causes of optic neuropathy should be ruled out when considering the diagnosis of low-tension glaucoma?
134. Are optic nerve head drusen usually unilateral or bilateral?
135. Do patients with optic nerve head drusen experience transient visual obscurations?
136. What are optic nerve head drusen?
137. What should be done if a patient presents with visual symptoms of optic neuropathy and is found to have optic nerve head drusen?
138. What is the most common congenital optic nerve anomaly?
139. What are the characteristics of optic nerve hypoplasia?
140. What conditions are associated with optic nerve hypoplasia?
141. What is an optic disk coloboma?
142. What conditions are associated with optic disk coloboma?
143. What are the characteristics of the “morning glory” disk anomaly?
144. What is the mechanism behind the morning glory disk anomaly?
145. What conditions are associated with the “morning glory” disk anomaly?
146. What is the mechanism of optic pit development?
147. What are the characteristics of an optic pit?
148. What are the characteristics of the tilted disk anomaly?
149. What is the usual field defect seen with myelinated retinal nerve fibers around the disk?

Neuro-ophthalmology Illustrated Chapter 8 – Optic Neuropathies 9

Questions:
101. What are the characteristics of hereditary optic neuropathies?
102. When should hereditary optic neuropathies be suspected?
103. What is the most common hereditary optic neuropathy?
104. What misdiagnosis is often made in dominant optic atrophy?
105. What is the typical disk appearance in dominant optic atrophy?
106. Can hereditary optic atrophies have other neurologic or systemic signs?
107. Are hereditary optic atrophies associated with degenerative or developmental diseases?
108. How is Leber hereditary optic neuropathy (LHON) inherited?
109. What are the clinical findings in Leber hereditary optic neuropathy (LHON)?
110. What can be associated with  Leber hereditary optic neuropathy (LHON?
111. Is there a genetic blood test for Leber hereditary optic neuropathy (LHON)?
112. Does spontaneous vision improvement occur in some patients with Leber hereditary optic neuropathy (LHON)?
113. What test should be done on patients confirmed as having Leber hereditary optic neuropathy (LHON)?
114. Which hereditary optic atrophy often has disk cupping in addition to bilateral temporal disk pallor?
115. What are the characteristics of Autosomal Dominant Optic Atrophy (DOA)?

Neuro-ophthalmology Illustrated Chapter 8 – Optic Neuropathies 8

Questions:
95. Do anterior and large intraorbital lesions produce optic disc swelling?
96. Do intracranial, intracanalicular, and posterior orbital compressive lesions typically produce disc swelling?
97. How is the presumed diagnosis of compressive optic neuropathy confirmed?
98. What are the characteristic findings of optic nerve sheath meningioma?
99. What are 7 characteristic findings of optic nerve glioma/pilocytic astrocytoma?
100. What are 6 characteristic findings of craniopharyngioma?

Neuro-ophthalmology Illustrated Chapter 8 – Optic Neuropathies 7

Neuro-ophthalmology Illustrated Chapter 8 – Optic Neuropathies 7

Questions:
85. How long after radiation does radiation optic neuropathy devel
86. What are the characteristics of radiation optic neuropathy?
87. In which race is arteritic ischemic optic neuropathy most commonly seen?
88. What is the typical age of onset of arteritic ischemic optic neuropathy?
89. What are the usual systemic symptoms associated with arteritic ischemic optic neuropathy?
90. Can visual loss be the only symptom of arteritic ischemic optic neuropathy?
91. Is visual loss in arteritic ischemic optic neuropathy usually severe?
91. What should recurrent episodes of transient monocular visual loss or transient diplopia suggest in an individual over 50?
93. Other than giant cell arteritis, what are causes of arteritic AION and PION?
94. In presumed arteritic ischemic optic neuropathy, should the results of a temporal artery biopsy be obtained before starting high dose systemic corticosteroid therapy?